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In this issue: Little Things Multiply Up: Hierarchical Structures by Tom McKeag, Small Worlds in a Big Space by Adelheid Fischer, The Systems View of Life: A Unifying Vision by Fritjof Capra and Pier Luigi Luisi, Portfolio by Rafael Araujo, Interview with Randy Olson and Brian Palermo, and The Systems View and Your Bio Toolbox by Curt McNamara.